Biology Open: The story so far…

Biology Open: The story so far…

It is hard to believe that, with the arrival of 2015, Biology Open (BiO) begins its fourth year of publication. We’d like to take this moment to look back on what we have learned since the first issue was published by The Company of Biologists in January 2012. BiO was launched with the aim of reducing the ‘pain to publish’ that many authors experience. By publishing all papers that address a va...

Curcumin: the story so far.

Curcumin is a polyphenol derived from the herbal remedy and dietary spice turmeric. It possesses diverse anti-inflammatory and anti-cancer properties following oral or topical administration. Apart from curcumin's potent antioxidant capacity at neutral and acidic pH, its mechanisms of action include inhibition of several cell signalling pathways at multiple levels, effects on cellular enzymes s...

MetateM: The Story so Far

METATEM is a simple programming language based on the direct execution of temporal logic statements. It was introduced through a number of papers [35,2,3] culminating in a book collecting together work on the basic temporal language [5]. However, since that time, there has been a programme of research, carried out over a number of years, extending, adapting and applying the basic approach. In p...

Estrogen and cognition: the story so far.

ESTROGEN is a complex gonadal hormone that reportedly exhibits numerous neurobehavioral effects in both human volunteers and animals. Evidence from basic science and clinical research demonstrates that estrogen can enhance cognitive function of healthy older women as well asthose with Alzheimer’s disease (AD) (1–3). Although the biology of estrogen strongly supports its neuromodulatory and neur...

Milestones in Transplantation : the Story so Far